human diploid skin fibroblasts Search Results


90
Coriell Institute for Medical Research human diploid skin fibroblasts ag1522
Proton-induced adaptive response in normal human cells. ( A ) Experiment schematic: Confluent normal human <t>fibroblast</t> cultures were first exposed to a priming radiation dose from energetic low-LET protons, followed 0, 6 or 24 h later by a challenge dose of high-LET iron ions. ( B ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in <t>AG1522</t> cells pre-irradiated with 20 cGy from 1-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). ( C ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 0.05-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). The data indicate that pre-exposure to a low dose of low-LET protons protects against DNA damage from a subsequent challenge from high-LET iron ions. * P < 0.05, ** P < 0.0001.
Human Diploid Skin Fibroblasts Ag1522, supplied by Coriell Institute for Medical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human diploid skin fibroblasts ag1522 - by Bioz Stars, 2026-03
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Coriell Institute for Medical Research human skin fibroblast cell line ago1522
Proton-induced adaptive response in normal human cells. ( A ) Experiment schematic: Confluent normal human <t>fibroblast</t> cultures were first exposed to a priming radiation dose from energetic low-LET protons, followed 0, 6 or 24 h later by a challenge dose of high-LET iron ions. ( B ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in <t>AG1522</t> cells pre-irradiated with 20 cGy from 1-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). ( C ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 0.05-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). The data indicate that pre-exposure to a low dose of low-LET protons protects against DNA damage from a subsequent challenge from high-LET iron ions. * P < 0.05, ** P < 0.0001.
Human Skin Fibroblast Cell Line Ago1522, supplied by Coriell Institute for Medical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human skin fibroblast cell line ago1522/product/Coriell Institute for Medical Research
Average 90 stars, based on 1 article reviews
human skin fibroblast cell line ago1522 - by Bioz Stars, 2026-03
90/100 stars
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90
Coriell Institute for Medical Research diploid human skin fibroblast strains
Proton-induced adaptive response in normal human cells. ( A ) Experiment schematic: Confluent normal human <t>fibroblast</t> cultures were first exposed to a priming radiation dose from energetic low-LET protons, followed 0, 6 or 24 h later by a challenge dose of high-LET iron ions. ( B ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in <t>AG1522</t> cells pre-irradiated with 20 cGy from 1-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). ( C ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 0.05-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). The data indicate that pre-exposure to a low dose of low-LET protons protects against DNA damage from a subsequent challenge from high-LET iron ions. * P < 0.05, ** P < 0.0001.
Diploid Human Skin Fibroblast Strains, supplied by Coriell Institute for Medical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/diploid human skin fibroblast strains/product/Coriell Institute for Medical Research
Average 90 stars, based on 1 article reviews
diploid human skin fibroblast strains - by Bioz Stars, 2026-03
90/100 stars
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Image Search Results


Proton-induced adaptive response in normal human cells. ( A ) Experiment schematic: Confluent normal human fibroblast cultures were first exposed to a priming radiation dose from energetic low-LET protons, followed 0, 6 or 24 h later by a challenge dose of high-LET iron ions. ( B ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 1-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). ( C ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 0.05-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). The data indicate that pre-exposure to a low dose of low-LET protons protects against DNA damage from a subsequent challenge from high-LET iron ions. * P < 0.05, ** P < 0.0001.

Journal: Journal of Radiation Research

Article Title: Low-dose energetic protons induce adaptive and bystander effects that protect human cells against DNA damage caused by a subsequent exposure to energetic iron ions

doi: 10.1093/jrr/rrv005

Figure Lengend Snippet: Proton-induced adaptive response in normal human cells. ( A ) Experiment schematic: Confluent normal human fibroblast cultures were first exposed to a priming radiation dose from energetic low-LET protons, followed 0, 6 or 24 h later by a challenge dose of high-LET iron ions. ( B ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 1-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). ( C ) Micronucleus formation (left panel) and micronuclei distribution (right panel) in AG1522 cells pre-irradiated with 20 cGy from 0.05-GeV protons ( 1 H) and challenged 0, 6 or 24 h later with 50 cGy of 1-GeV/u iron ions ( 56 Fe). The data indicate that pre-exposure to a low dose of low-LET protons protects against DNA damage from a subsequent challenge from high-LET iron ions. * P < 0.05, ** P < 0.0001.

Article Snippet: Apparently normal human diploid skin fibroblasts (AG1522) were obtained from the Genetic Cell Repository at the Coriell Institute for Medical Research (Camden, NJ).

Techniques: Irradiation